Symptoms of Pleural Mesothelioma The initial symptoms of pleural mesothelioma include chest pain, shortness of breath, slight fatigue and weight loss. Because these symptoms mirror those of less serious illnesses, such as pneumonia or the flu, doctors often misdiagnose the cancer in its early stages. Unfortunately, many of the more serious symptoms, such as painful breathing, coughing blood and difficulty swallowing, aren�t noticeable until the cancer has reached its later stages, when treatment options are usually more limited. Pleural mesothelioma symptoms can include: Shortness of breathCoughHoarsenessPain in the lower back or side of the chestFatigueFeverSweatingWeight lossDifficulty swallowingSwelling in the face and arms Other signs of mesothelioma can include certain benign asbestos-related diseases. For example, studies show people with pleural plaques (areas of fibrous thickening on the lung's lining that can become calcified) are at an increased risk of developing pleural mesothelioma. Pleural thickening is another benign condition that sometimes develops before PM. Asbestosis is a chronic respiratory disease characterized by scarring and inflammation in the lungs. Approximately 15 percent of people with asbestosis develop pleural mesothelioma.

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